Evidence about the impact of chemicals on human, environmental and ocean health is mounting. Synthetic chemicals are in our food, furniture, toys, clothes, cosmetics and medicine, and demand is showing no sign of ceasing. Global chemicals manufacturing is increasing by 3.5% annually and expected to double by 2030. At the same time, deaths due to chemicals and pollutants have grown by over 66% since 2000—a figure that is likely an underestimate, since only a fraction of the thousands of manufactured synthetic chemicals have been properly tested for safety and toxicity, leaving their effect on human health and the environment unquantifiable. Some estimates place chemicals as responsible for about 6% of the world’s disease burden and 8% of all deaths.
Human health is damaged in myriad ways, including endocrine disruption. This affects the production and regulation of hormones, leading to a cell’s normal response being initiated at the wrong time or to an excessive extent. In this case, it stops the correct activity of the cell by preventing the hormones from binding to their receptors, interfering with the metabolic processes in the body by affecting the synthesis and breakdown of natural hormones.